HPVTyper: A Software Application for Automatic HPV Typing via PCR-RFLP Gel Electrophoresis
نویسندگان
چکیده
The cervical cancer is currently the most prominent case of association between HPV and cancer. The persistent infection of the anogenital tract by a group of HPV types has been proved to be the main causal factor of cervical cancer (Bosch et al., 2002; Walboomers et al., 1999). This group of cervical cancer related types currently includes 30 to 40 types. However, not all the types in the group induce the same risk for the development of cervical cancer. In fact, virologists have classified the aforementioned types with respect to their oncogenic activity as low-risk, high-risk, and potentially high-risk (Muñoz et al., 2003), while other HPV types remain unclassified.
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